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d'Annunzio Chieti and Pescara, Italy Reviewed by Fahad S Alshehri, Umm Al Qura University, Saudi Arabia Juan Yugar, Faculdade de Medicina de So Jos do Rio Preto, Brazil Luis Gustavo Sedenho-Prado, State University of Campinas, Brazil Updates Copyright 2026 Wen
It can aid weight loss
People who had bariatric surgery lost around five times more weight than those using GLP-1 injections over two years Real-world weight loss from GLP-1 drugs was far lower than results reported in clinical trials, partly due to high dropout rates The findings highlight surgery as the most effective and durable option for severe obesity, while medications still help some people Injectable weight loss drugs such as semaglutide and tirzepatide have attracted huge attention, but new real-world data suggest they deliver far less weight loss than surgery outside clinical trials
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